Welcome to your new favorite weeknight meal! This Mexican Ground Beef Casserole is the perfect solution for busy evenings when you crave something hearty, flavorful, and incredibly satisfying. We’re talking layers of seasoned ground beef, savory enchilada sauce, sweet corn, black beans, and a generous blanket of melted cheese. It’s a true one-pan wonder that brings the vibrant tastes of Mexico to your table with minimal effort. Forget complicated recipes; this dish is all about simple ingredients and big results.
This recipe was born from a desire to create a family-friendly meal that is both delicious and easy to assemble. It’s incredibly versatile, perfect for potlucks, and the leftovers are just as amazing. Let’s dive in and make a dish that will have everyone asking for seconds.

Why This Is the Best Mexican Ground Beef Casserole
You’re going to absolutely love this recipe, and here’s why it stands out from the rest. It’s designed to be the most flavorful and straightforward casserole you’ll ever make.
- Effortless Preparation: With simple steps and common ingredients, this dish comes together in no time. It’s the ideal meal for those hectic weeknights.
- Packed with Flavor: We use a blend of taco seasoning and rich enchilada sauce to create a deep, savory flavor profile that perfectly complements the ground beef and vegetables.
- Crowd-Pleasing: This casserole is a guaranteed hit with both kids and adults. Its cheesy, comforting nature makes it a go-to for family dinners.
- Customizable: Feel free to get creative! You can easily add your favorite toppings or swap ingredients to suit your family’s tastes. For a lower-carb version, check out this Keto Ground Beef Casserole (coming soon).
Ingredients You’ll Need
This recipe uses simple, easy-to-find ingredients to create a truly spectacular meal. Here’s what you’ll need to gather.
- Ground Beef: We recommend using 85/15 ground beef for the perfect balance of flavor and tenderness.
- Onion & Garlic: These aromatics form the essential flavor base of the casserole.
- Taco Seasoning: Use your favorite store-bought packet or a homemade blend for that classic taco flavor.
- Enchilada Sauce: A good quality red enchilada sauce brings everything together with its rich, slightly spicy taste.
- Black Beans: Be sure to rinse and drain them well.
- Corn: Canned or frozen corn adds a touch of sweetness and texture.
- Corn Tortillas: These will be layered throughout the casserole, soaking up all the delicious sauce.
- Shredded Cheese: A Mexican blend or cheddar cheese works perfectly.
Step-by-Step Instructions
Follow these simple steps to create your delicious Mexican Ground Beef Casserole. It’s a straightforward process that delivers a stunning final dish.
- Brown the Beef: In a large skillet, cook the ground beef with the chopped onion until the meat is browned and the onion is soft. Drain any excess grease.
- Add Flavor: Stir in the minced garlic and taco seasoning, cooking for another minute until fragrant.
- Combine Ingredients: Add the enchilada sauce, black beans, and corn to the skillet. Let it simmer for 5 minutes to allow the flavors to meld together.
- Assemble the Casserole: Spread a thin layer of the meat mixture in the bottom of a 9×13 inch baking dish. Arrange a layer of corn tortillas on top. Repeat the layers, finishing with a final layer of the meat mixture.
- Bake to Perfection: Sprinkle the shredded cheese evenly over the top. Bake in a preheated oven at 375°F (190°C) for 20-25 minutes, or until the casserole is bubbly and the cheese is golden brown.

Tips for Success and Variations
Want to take your casserole to the next level? Here are some expert tips and fun variations to try.
Helpful Tips
- Don’t Overcrowd the Pan: Use a 9×13 inch pan to ensure the casserole cooks evenly.
- Let it Rest: Allow the casserole to rest for 5-10 minutes after baking. This helps it set and makes it easier to serve.
- Fresh Toppings: Serve with fresh toppings like sour cream, cilantro, diced avocado, or jalapeños to add a burst of flavor and texture. If you love ground beef dishes, you might also enjoy this easy Ground Beef and Potato Casserole (coming soon).
Flavor Variations
- Add Some Spice: For a spicier kick, add a can of diced green chiles or a pinch of cayenne pepper to the meat mixture.
- Change the Protein: This recipe works wonderfully with ground turkey or chicken as well.
- Add Rice: Mix in a cup of cooked rice with the beef mixture for an even heartier casserole.
How to Store and Reheat
This Mexican Ground Beef Casserole is perfect for meal prep. Store leftovers in an airtight container in the refrigerator for up to 4 days. You can also freeze individual portions for a quick and easy meal later. To reheat, simply microwave until hot or bake in the oven at 350°F (175°C) until warmed through.
What to Serve with Your Casserole
While this casserole is a complete meal on its own, it pairs beautifully with a simple side salad, a scoop of Spanish rice, or a side of cilantro-lime cauliflower rice. For another fantastic ground beef recipe, give our Cheesy Ground Beef Casserole (coming soon) a try!
Frequently Asked Questions
Yes, this casserole freezes beautifully. Assemble the casserole but do not bake it. Cover it tightly with both plastic wrap and foil and freeze for up to 3 months. Thaw overnight in the refrigerator before baking as directed.
Absolutely! You can assemble the entire casserole, cover it tightly, and refrigerate it for up to 24 hours before baking. You may need to add 5-10 minutes to the baking time.
To make this recipe gluten-free, simply ensure you use certified gluten-free corn tortillas and check that your enchilada sauce and taco seasoning are also gluten-free.
This casserole is very versatile! You can easily substitute the ground beef with ground turkey, ground chicken, or even a plant-based crumble for a vegetarian option.
We love serving this casserole with a variety of toppings! Some popular choices include sour cream or Greek yogurt, fresh cilantro, diced avocado, guacamole, salsa, and sliced jalapeños.
Your New Favorite Weeknight Meal
This Mexican Ground Beef Casserole is more than just a recipe; it’s a solution for busy families who refuse to compromise on flavor. It’s warm, cheesy, and packed with savory goodness that will bring everyone to the table. We hope you love it as much as we do!
If you make this recipe, be sure to leave a comment and share your creation on Pinterest! We can’t wait to see it.

Mexican Ground Beef Casserole

Mexican Ground Beef Casserole: The Ultimate Weeknight Dinner
Ingredients
Equipment
Method
- Preheat your oven to 375°F (190°C). Lightly grease a 9x13 inch baking dish.
- In a large skillet over medium-high heat, cook the ground beef and chopped onion until the beef is browned. Drain off any excess grease.
- Stir in the minced garlic and taco seasoning. Cook for 1 minute more until fragrant.
- Pour in the enchilada sauce, and add the rinsed black beans and drained corn. Stir to combine and let the mixture simmer for 5 minutes.
- Spread about one-third of the meat mixture onto the bottom of the prepared baking dish. Arrange a layer of tortilla quarters over the meat mixture. Repeat the layering twice more, ending with the meat mixture on top.
- Sprinkle the shredded cheese evenly over the top layer.
- Bake for 20-25 minutes, or until the cheese is melted and bubbly and the casserole is heated through.
- Let the casserole rest for 5-10 minutes before serving. Garnish with fresh cilantro, sour cream, or avocado if desired.
Notes
Freezing: This casserole freezes well. Assemble but do not bake, then cover tightly and freeze for up to 3 months. Thaw in the refrigerator overnight before baking as directed.
Spice it up: Add a chopped jalapeño with the onion for extra heat.